What was Madonna’s last #1 song on the Billboard Hot 100? Here’s a hint. It was all the way back in the year 2000. The answer is… “Music”. From the album of the same name, “Music” raced up the airplay charts and the sales charts immediately after release. Its infectious beat was an instant club favorite. Now, that may be Madonna’s last #1, but it wasn’t her last hit. She made the top ten in 2012 with “Give Me All Your Lovin’”. Her last release, “Popular” from 2023 hit the top ten in Japan, the UK, Canada, and Australia. That song’s highest chart position in the US was #43.